The 5 Most Important Supplements

SOURCE: Yahoo Shine

I usually take a fistful of nutritional supplements every day. In fact, most people are speechless when they see my daily regimen.

I also travel with them — putting each day’s allotment into plastic bags and stuffing them in my suitcase.

But I recently left the States for a four-week medical mission in Tibet and my gear was limited to 50 pounds. So there won’t be room for my usual supplement supply.

So I’ve had to decide…

“If I could only take five supplements, what would they be?”

I only had room for five supplements per day, so they had to be the really important ones.

So here they are. By the way… these are also the ones I recommend you begin with if you’re just starting out — or the ones you can cut back to if you need to save money. Anyway, here goes…

1. A high-quality multi-vitamin

Topping the list is an excellent quality multi-vitamin. This is essential because a multi “fills in the blanks” of your diet (no matter how good it is), so you’re not running dangerously low on the essential nutrients your body needs for optimal functioning.

Be sure to avoid the TV-advertised one-a-days you find in your local drugstore. These are nearly worthless because their ingredients are based on the “bare minimum” official Recommended Daily Allowance (RDA), now upgraded to the Recommended Daily Intake (RDI).

The RDA evolved from the old Minimum Daily Requirement (MDR) set by the government. This means the nutrients in most of the popular multis contain the minimum doses necessary to prevent nutritional -deficiency diseases, such as scurvy (vitamin C), beriberi (vitamin B1), and others. This certainly is not how to guarantee optimal health.

These mainstream multis are notoriously feeble. For example, Consumer Reports recently concluded that Centrum is the worst vitamin for seniors in its class. (There goes that advertising revenue!)

Consumer Reports also found that The Vitamin Shoppe’s One Daily failed to dissolve in a simulated stomach environment, while containing less vitamin A than its label claims.

You can avoid this pitfall by sticking to high-quality, bioavailable multivitamins that are reasonably priced and lab-tested. One of my favorites is Ultimate Daily Support from Real Advantage, formulated by Dr. William Campbell Douglass. It’s a terrific multi that contains a broad list of vitamins, minerals, antioxidants, amino acids, and enzymes that easily are absorbed and quickly bioavailable. This is the multinourishing my body in Tibet.

Another top-notch product is Forward Multi-Nutrient , formulated by Dr. Julian Whitaker, a friend and associate I’ve known for almost 20 years. Julian is a pioneer in the orthomolecular field and alternative medicine and has done so much to legitimize natural healing. He’s also a living legend who was mentored by Dr. Linus Pauling.

2. A quality omega-3 supplement

Fish oil is today’s bestselling supplement — and with good reason. The EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) in omega-3 fish oil have profoundly positive effects on human health.

DHA slows your liver’s production of undesirable triglycerides, making it extremely protective against heart disease and diabetes.

In addition, fish oil is incredibly effective at reducing inflammation. It accomplishes this by triggering the release of prostaglandins (natural substances that regulate immunity, inflammation, blood clotting, brain function, plus a host of other essential functions).

There’s not enough room here to list all the healing effects of omega-3. The highlights include: Healing blood vessel walls … keeping the blood thin (thus minimizing clotting) flowing smoothly … lowering blood pressure … stabilizing blood sugar … and brightening your mood.

The American Heart Association recommends a daily dose of 500-1,000 mg of DHA and EPA from fish oil to reduce heart disease — but I think this is a paltry dose. I prefer to take 6,000 to 9,000 iu daily in three equal doses — and find this really helps my arthritis.

There’s just one problem. The huge demand for fish oil is wreaking havoc on marine life. Overfishing is depleting fish stocks and the oceans are on the brink of crisis.

Even oils extracted from krill (tiny, omega-3-rich crustaceans) are troublesome. That’s because krill are at the bottom of the ocean’s food chain — and larger fish depend upon them for life. Harvesting krill deprives all fish of their main food supply.

This is why I prefer to get my omega-3 from marine phytoplankton (also known as “micro algae”) these days.

Phytoplankton is the plant-based omega-3 food source that supplies krill and other fish with EPA and DHA. Raised in large, land-based tanks, phytoplankton is free of mercury contaminants, heavy metals, and ocean pollution. Its good stuff — and you’re not depriving fish of their food supply.

3. Co-enzyme Q-10

CoQ-10 (also known as ubiquinol) is a nutrient produced by the “energy factories” in your cells called mitochondria. Taking a CoQ-10 supplement boosts the way your cells produce and use energy. It also helps your body burn fat … improves cholesterol ratios … boosts your physical energy levels … and improves thyroid and pancreas functions.

By the way, statins — the widely — (or is it “wildly”?) prescribed cholesterol-lowering drugs — actually deplete your body’s natural CoQ-10. Statins block production of cholesterol in the liver, where CoQ-10 is also manufactured. Without sufficient CoQ-10, statins can cause liver damage … irregular heartbeat … muscle weakness … leg cramps … heart attack and stroke (the two potentially fatal conditions that statins are supposed to prevent).

Other medications also can limit your body’s production of CoQ-10, including: Diabetes drugs … antidepressants … female hormone replacement therapy … and blood pressure meds. If you take any of these, you definitely need to supplement with CoQ-10.

When shopping, labels may read “CoQ-10” or “Coenzyme Q-10”, but the more active form will be labeled “QH” or “ubiquinol.” This is a stronger form of CoQ-10, though purchasing that version isn’t essential, especially if price is an issue. Take 100 mg two or three times twice per day, because your body can’t metabolize higher doses.

4. Magnesium citrate

You’ve been hearing about calcium and bone health forever — but did you know that magnesium and calcium are like conjoined twins? Calcium can’t even be absorbed unless magnesium is present. Without it, calcium is much less effective in maintaining your bones and regulating your nerve and muscle tone.

In fact, new research shows that Americans need far more magnesium than the current RDI — and that you should really be consuming twice as much magnesium as calcium for optimal health.

Magnesium may be the most important mineral you can take because it’s a key player in 300 essential bodily functions, and is used by all of your organs. It activates enzymes … powers your energy … and helps your body absorb vitamin D, potassium, and zinc.

The majority of Americans are magnesium-deficient due to the low-quality, processed foods in the typical American diet. Produce grown in mineral-depleted soil won’t provide much magnesium, either.

If you have blood sugar issues, you should know that magnesium helps regulate blood sugar and insulin activity. In addition, magnesium’s ability to relax muscles and nerves makes it one of your best allies in the battle against anxiety … hypertension … restless leg syndrome … sleep disorders … and abnormal heart rhythm.

Consuming magnesium supplements can be challenging, as they tend to be large and difficult to digest. That’s why I like Natural Calm , a fruit-flavored magnesium powder that mixes easily in water. I take it in the evening because of its relaxing effect. Start with a low dose, because it can loosen your stools (not necessarily a bad thing if constipation is a problem). Another alternative is a topically-applied magnesium chloride liquid spray that’s absorbed through the skin, which won’t affect your bowels.

5. Sunshine vitamin D

This is rapidly becoming the miracle vitamin of our time. Every week, it seems, there’s a new finding about D’s marvelous benefits. Most Americans are badly deficient in vitamin D because doctors consider the sun our enemy — and your skin converts solar rays into this essential vitamin.

Numerous studies show that this amazing vitamin is protective against all cancers (even skin cancer and melanoma!) … strengthens bones … prevents and even heals diabetes … protects against heart disease … lowers blood pressure … reverses depression … and elevates mood.

Whenever you can, spend 10-20 minutes sunbathing — without sunscreen. (Your body transforms sunshine into all the vitamin D it needs.) If your access to sunlight is limited by season or geographic location, take 2,000-5,000 iu of a good quality vitamin D supplement daily. (The elderly and African-Americans need higher doses.) Official recommendations call for a scant 600 iu, which is far too low. Just make sure you purchase vitamin D3 (not D2) because the D3 form is 87% more potent than vitamin D2.

No more “supplement overwhelm”

Taking these five supplements should cover all the important bases and provide your body with optimal nutrition (provided you’re eating a healthy diet).

Now I’d like to hear from you. Do you have a favorite supplement that I’ve missed? Do you have a story about how a particular supplement or herbal remedy turned your health around?

Please share whatever’s on your mind about nutritional supplements here so we can all benefit from your experience.

Ten Foods That Will Improve Your Mood

There are lots of foods that bring a smile to my face—cookies, veggie burritos, and peanut butter oatmeal (trust me, it’s delicious) are just a few. But it turns out some foods don’t just please the palate; they stimulate the brain and make us physically happy, too. When we need a little pick-me-up, we should skip the cookies (as yummy as they are, the sugar rush destabilizes our moods) and seek out these foods instead.


Spinach
This leafy green is loaded with the B vitamin folate, which has been linked to depression when levels are too low. B vitamins help the brain produce serotonin, a neurotransmitter that affects mood and behavior.


Turkey
Turkey’s full of tryptophan, an amino acid that the body uses to create mood-regulating serotonin and melatonin. Since our bodies don’t produce tryptophan naturally, we must get it from food sources. For a non-poultry vehicle for the amino acid, try pineapple, cottage cheese, or lobster.


Walnuts
Researchers at the Massachusetts based McLean Hospital found that rats’ moods improved when given an injection of omega-3 fatty acids. Walnuts and ground flaxseeds (they have to be ground for the body to absorb the nutrients) are the best non-animal source of omega-3s.


Milk/Non-Dairy Milk
Milk products and vitamin-fortified non-dairy products (soy milk, almond milk, etc.) are rich in vitamin D, which can increase serotonin production and has been linked to reducing depression in some people. A 2008 study published in the Journal of Internal Medicine found that vitamin D alleviated some depressive symptoms.


Soy
Like turkey, soy products such as tofu and edamame have high levels of tryptophan. Soybeans also rank low on the glycemic index, meaning they don’t spike energy levels too quickly and won’t cause a mood crash later.


Salmon
If you’re not a vegetarian, the best way to get a good dose of omega-3s into your diet is through salmon. Not a fan of salmon? Tuna and herring boast a decent amount of the fatty acids as well.


Beans
Protein- and fiber-filled legumes like black beans and lentils are also packed with iron, an essential mineral that combats lethargy and gives us energy.


Chocolate
Few people would frown after popping a square of chocolate into their mouths, but it’s not just because it tastes so good—chocolate causes the brain to release endorphins and can boost serotonin levels and it contains compounds, like phenylethylamine, that act as mild stimulants. However, plain old milk chocolate won’t do; opt for 70 percent dark chocolate to ensure maximum health benefits.


Carbohydrates
Foods rich in carbohydrates also affect serotonin levels in the body, but simple carbs—those with white flour as the primary ingredient—increase insulin production so rapidly that the feel-good vibes we get after ingesting them quickly turn into grumpiness. Stick to whole grains like oats, brown rice, and whole wheat bread, all of which contain B vitamins as well.


Bananas
Besides being a potassium powerhouse, eating bananas adds a hefty amount of tryptophan to our diets. In a study at Oxford University, researchers found that women recovering from depression who were deficient in tryptophan had a higher chance of regressing back to depressive states. Bananas are a great source of iron, too.


What makes certain foods mood-elevating seems based on whether they contain essential ingredients such as omega-3 fatty acids, tryptophan, vitamin D, or B vitamins. Unfortunately, what we crave when we’re depressed usually isn’t flaxseeds or salmon. Our cravings are usually in the form of French fries and donuts, foods that comfort us briefly but make us feel even more sluggish and moody afterward. But if we learn to reach for these mood-boosting foods instead, maybe we can banish the blues before they even start.

SOURCE: RefreshingNews

Cancer Feeds on Fructose, America’s Number One Source of Calories

Anthony Gucciardi
Activist Post

High-fructose corn syrup is the primary source of calories in the United States. In addition to containing mercury, a known carcinogen, cancer cells actually feed on high-fructose corn syrup after it is metabolized by the liver. A new study, published in the Expert Opinion on Therapeutic Targets, examined the link between refined sugar and cancer. The results add further evidence to the reports of many health experts and scientific studies that have drawn the connection between excess sugar consumption and the development of cancer.

The researchers highlighted the numerous ways in which fructose directly contributes to cancer risk and other health problems, including:
  • DNA damage
  • Inflammation
  • Altered cellular metabolism
  • Increased production of free radicals

God's Dietary Laws

CLEAN AND UNCLEAN:

Abolished in the New Testament?

READERS: The purpose of this article is not to condemn or insult those who hold to the standard Christian teaching that God�s dietary laws are abolished under the New Covenant. The purpose of the article is to examine the New Testament passages which are commonly quoted in support of this teaching, and to show that these passages do not really teach what most Christians think they teach.

The Bible tells us that there was a distinction between clean and unclean animals for at least a thousand years before the Torah was given to Moses. This distinction between clean and unclean animals is mentioned in Gen. 7:2 and 8:20, in the account of Noah�s Flood. Genesis does not tell us which animals were clean and which were unclean, but it is obvious that Noah knew the difference.

About a thousand years later, when the Torah was given to Moses, God went into great detail and listed which animals were clean (kosher; fit for human consumption) and which were unclean (non kosher; not fit for human consumption). The entire 11th chapter of Leviticus is devoted to this subject. A shorter version of the list is repeated in Deuteronomy 14.

Orthodox Jews take these commandments literally, and do not eat pork, shellfish, or any of the other forbidden meats. Christians, on the other hand, feel that there is nothing wrong with eating these things. Many Christians (and doctors and nutritionists, too) will admit that people would be a lot healthier if they followed God�s dietary laws, and a small number of Christians actually do make an effort to avoid meat from unclean animals. But the great majority of Christians do not view the dietary laws as Divine commandments which ought to be obeyed.

A number of arguments have been put forth to support the standard Christian position. Probably the oldest argument is drawn from the Second Century Epistle of Barnabas. The writer spiritualizes the dietary laws, and says that the various unclean animals represent different types of behavior in which a Christian should not engage. While there may be alegitimate analogy here (Christians shouldn�t behave like pigs, etc.), the analogy fails to prove that God does not want His people to take the commandments literally and abstain from these meats.

Of course the most common argument against the validity of the dietary laws is the claim that God abolished them in the New Testament. This claim is often coupled with the idea that God originally gave the dietary laws because people didn�t have refrigeration in Old Testament times. I�ve got news for you. People didn�t have refrigeration in New Testament times, either. If God�s dietary commandments had anything at all to do with the absence of refrigeration, He wouldn�t have "abolished" them until about a hundred years ago, when refrigeration was invented.

There are six New Testament passages which can give the impression that God did, indeed, abolish the dietary commandments which He established in the Old Testament. However, a close look at these passages reveals that they really prove no such thing. The only way a person can use any of these passages to "prove" the nullifying of the dietary laws is to: 1) ignore the context of the passage; 2) ignore the historical background of the passage; 3) ignore what the rest of the Bible says about the subject; 4) ignore the implications and logical conclusions of this theological position.

Before we look at the six New Testament passages, let us consider two important questions:

1) Were the dietary laws, as written in the Bible, man-made traditions, or were they commandments of God? Bible-believers must admit that these were commandments which God expected His people to obey;

2) Did the Son of God teach His disciples to disobey the commandments of God? Some might think this is a ridiculous question, yet this is exactly what some Christians actually believe Jesus did in Matt. 15, the first passage we will look at.More

Realted:

A List of Clean Fish (Edible according to God)

PAUL AND UNCLEAN MEATS

Immune System Protects Against Flu, Not Vaccines

Anthony Gucciardi
Activist Post

Preventing the flu may not come down to hand sanitizers and risky vaccinations. A new study has found that only half of all individuals affected with the flu virus actually get sick, highlighting the necessity of a powerful immune system that is able to respond to the flu virus appropriately.

The
study comes from the University of Michigan, where researchers infected 17 healthy individuals with the flu, about half of which reported actually getting sick as a result. The other half felt completely fine.

The average American touches around 300 different surfaces every 30 minutes, demonstrating that it is virtually impossible to avoid coming in
contact with a virus that may invade your body. Instead, a boosted immune system will be able to defend against potentially-harmful viruses that seek to make you ill. You cannot prevent coming in contact with bacteria and viruses, but you can certainly establish a biological defense against them.

Natural Cancer-Fighting Spice Reduces Tumors by 81%

Anthony Gucciardi
Activist Post

Used in the ancient Chinese and Indian systems of medicine, curcumin is a naturally powerful anticancer compound that has been found to decrease brain tumor size in animals by 81 percent in more than 9 studies. A derivative of turmeric, curcumin is the pigment responsible for turmeric’s yellow-orange color. Each 100 grams of turmeric contains around 3 to 5 grams of curcumin, though turmeric is a also very powerful on its own. New studies are shedding light on curcumin, and illuminating its numerous benefits on cancer and other diseases.

Researchers experimenting with curcumin in the treatment of a fatal brain cancer known as glioblastoma (GBMs) published their groundbreaking findings in the Journal of Nutritional Biochemistry in July.

Prescription Drug Deaths Now Outnumber Traffic Fatalities in U.S.

Anthony Gucciardi
Activist Post

In 2009, drugs exceeded the amount of traffic-related deaths, killing at least 37,485 people nationwide. According to information provided by the U.S. Centers for Disease Control and Prevention, the very pharmaceuticals that are prescribed to treat life-endangering conditions are now ending lives.

The death toll is partially due to an increase in mental illness medication known as psychotropics, which have been criticized by health experts as being oftentimes unnecessarily prescribed. The pills, given to patients to prevent suicide thoughts and tendencies, may actually lead to suicidal thoughts and suicide.

California Bans Unvaccinated Children from Class

Anthony Gucciardi
Activist Post

If your child hasn’t received the whooping cough vaccine, he or she is now banned from attending class at many California schools. Despite legitimate religious or personal health reasons for rejecting the whooping cough vaccine, your child simply cannot attend class. Due to a law that requires all students entering grades seven through 12 be vaccinated, the San Francisco school district has begun sending home children who do not have proof of receiving the whooping cough vaccination.

Proof of vaccine ineffectiveness

Why are schools afraid of unvaccinated children spreading the disease to vaccinated children if the whooping cough vaccine is truly effective? How could an unvaccinated child spread the disease to someone who has already received the whooping cough vaccine?

Kids Drinking Raw Milk Have 40% Less Asthma and Allergies: Study

David Michael Augenstein
Living Food Journal

Reuters, Fox and other media outlets reported September 13 about a large European raw milk study published at the Journal of Allergy and Clinical Immunology, online August 29, 2011, showing kids who drink raw milk are 41% less likely to suffer from asthma and allergies. The study included 8334 school-aged children, and 7606 of them provided serum samples to assess specific immunoglobulin E (IgE) levels. Over 800 cow’s milk samples were collected at the participants’ homes. Reuter’s article stated:

Compared with kids who only drank store-bought milk, those who drank raw milk had a 41-percent reduction in their odds of developing asthma. They were also only about half as likely to develop hay fever — even after accounting for other factors that might be relevant. On the other hand, those who drank boiled farm milk had no less asthma than those who drank store milk. The protective effect was linked to so-called whey proteins in the milk, such as BSA and alpha-lactalbumin. Pasteurization remains an effective tool to inactivate harmful microorganisms but may simultaneously destroy whey proteins.
The results of this study brings up two other very serious questions rarely posed: 1) What other diseases and disorders are caused by regular pasteurized, homogenized milk with synthetic chemical additives? and 2) What other health benefits can be realized from including raw milk as part of a well-rounded diet of whole, fresh foods?

Read Full Article

Flashback: The Hepatitis B Vaccine is Linked to Infant Death, Multiple Sclerosis and Autoimmune Disorders


Anthony Gucciardi
Activist Post

The hepatitis B vaccine has been approved for all U.S. infants at birth, but is it really safe? For a “preventative” vaccination, the amount of complications associated with the hepatitis B vaccination are quite shocking. In fact, a number of peer-reviewed studies have found a relationship between the hep B vaccination and infant deaths both in the U.S. and Europe. With links to sudden infant death syndrome (SIDS), multiple sclerosis, and numerous chronic autoimmune disorders, some doctors are speaking out against the dangers of the hep B vaccine.

'Huge' results raise hope for cancer breakthrough

In a potential breakthrough in cancer research, scientists at the University of Pennsylvania have genetically engineered patients' T cells — a type of white blood cell — to attack cancer cells in advanced cases of a common type of leukemia.

Two of the three patients who received doses of the designer T cells in a clinical trial have remained cancer-free for more than a year, the researchers said.

Experts not connected with the trial said the feat was important because it suggested that T cells could be tweaked to kill a range of cancers, including ones of the blood, breast and colon.
"This is a huge accomplishment — huge," said Dr. Lee M. Nadler, dean for clinical and translational research at Harvard Medical School, who discovered the molecule on cancer cells that the Pennsylvania team's engineered T cells target.

Findings of the trial were reported Wednesday in two journals.
To build the cancer-attacking cells, the researchers modified a virus to carry instructions for making a molecule that binds with leukemia cells and directs T cells to kill them. Then they drew blood from three patients who suffered from chronic lymphocytic leukemia and infected their T cells with the virus.
When they infused the blood back into the patients, the engineered T cells successfully eradicated cancer cells, multiplied to more than 1,000 times in number and survived for months. They even produced dormant "memory" T cells that might spring back to life if the cancer was to return.

MORE>>>>>>>

Potatoes, especially purple, may help lower blood pressure

USA Today — French fries and potato chips may have given potatoes a bad rap, but new research finds the lowly tuber — when cooked correctly — may actually be good for the heart.
A small, pilot study suggests that a couple of servings of potatoes per day can lower blood pressure as much as oatmeal without causing weight gain, researchers said.
Joe Vinson, a professor of chemistry at the University of Scranton in Pennsylvania, analyzed 18 patients who ate six to eight small purple potatoes twice daily for a month and found their systolic and diastolic blood pressures (the top and bottom numbers on a blood pressure reading) dropped by 3.5 and 4.3 percent, respectively.

Most patients were either overweight or obese, and many were already taking medications for high blood pressure during the study, which was funded by the U.S. Department of Agriculture and was to be presented Wednesday at the national meeting of the American Chemical Society in Denver. Experts note that research presented at scientific meetings is preliminary and has not yet been peer-reviewed.
Vinson pointed out that potatoes can be a healthy food when they’re not in the form of French fries or chips, or covered in high-fat toppings such as cheese and sour cream.
Purple ones, in particular, have high amounts of antioxidants, although red-skinned or white potatoes may have similar effects, he said.

The golf ball-sized potatoes used in the study were microwaved, which Vinson called a “benign” cooking method that doesn’t add fat or calories or destroy healthy substances in potatoes.
“Everyone thought potatoes were just a starch and pretty much nothing else,” said Vinson, explaining spuds’ poor nutritional reputation. “I was surprised . . . a very large proportion (of participants) were taking medications and still we had a drop in blood pressure.”
Read More >>

#Six and Diabetes: Jay Cutler On Numbers

As an NFL quarterback, Jay Cutler makes his living putting a football into the hands of an open receiver before getting slammed to the ground by a huge defensive lineman. It's a stressful occupation, all about timing, a little luck, and seeing the big picture in a split second.

So when Cutler lost 35 pounds and felt continually tired during April workouts for the 2008 season with the Denver Broncos, he wrote it off as stress-related. When a team trainer pulled him aside after a routine physical, Cutler never saw it coming.

"I think you need to see a doctor," the trainer told the 25-year old quarterback, pointing to a blood sugar of 550. "I think you have type 1 diabetes." Cutler remembers how the conversation ended: "Everything is going to be OK." Read more...

Foods That Fight Erectile Dysfunction

Can you certain nutrients boost your sexual performance? Find out which foods may prevent erection problems — and how they work.



Type 2 Diabetes and Sleep Troubles

Having type 2 diabetes and trouble sleeping create the ultimate catch-22: You need sleep to stay healthy, yet the condition makes it hard to get a good night's sleep. Here's some help.

Sleep is important for everyone, but it’s especially important when your body experiences changing blood sugar levels and other symptoms of type 2 diabetes. “Sleep deprivation causes changes in the effectiveness of the body's control of appetite, which can lead to weight gain, higher blood sugar, and increased resistance to insulin,” says Richard Castriotta, MD, director of the division of pulmonary, critical care, and sleep medicine at the University of Texas Health Science Center at Houston.

Diabetes and sleep

Although sleep is very important when you’re experiencing symptoms of type 2 diabetes, you may find you can’t sleep when you need it most. One explanation for the problem seems to be the connection between diabetes and sleep apnea. Sleep apnea is a condition that’s characterized by periods of halted breathing while you’re asleep, which wakes you up repeatedly throughout the night, leaving you fatigued and not well rested in the morning.

Both type 2 diabetes and sleep apnea are health concerns that are linked to obesity, so experts have long recognized a connection between the two. But only recently has it been realized how closely these conditions are tied to one another. “There’s much more interrelation between the two conditions than we thought,” says Betul Hatipoglu, MD, a physician in the Cleveland Clinic’s department of endocrinology, diabetes, and metabolism. “In fact, one may actually contribute to causing the other, and vice versa. Recent studies have shown that sleep apnea actually increases insulin resistance, hunger, and other type 2 diabetes symptoms,” Dr. Hatipoglu says. “Other studies have shown that treating sleep apnea also improves the symptoms of type 2 diabetes.”

Other Sleep Issues You Might Face

Another problem that disrupts sleep is frequent urination, a common symptom of type 2 diabetes. You can’t sleep if you have to keep getting up to go to the bathroom. Hatipoglu says this problem is usually tied to high blood pressure, which is also common with type 2 diabetes. As your blood pressure goes up throughout the night, the need to urinate increases. “If this occurs more than once a night, we view it as an issue that needs to be treated,” Hatipoglu says.

Having type 2 diabetes may also lead to other disorders that make it harder to sleep. “In addition to sleep apnea, people with type 2 diabetes are at increased risk for restless leg syndrome (RLS) and periodic limb movements in sleep (PLMS), as well as neuropathy and pain-associated sleep disruption,” Dr. Castriotta says. “RLS causes difficulty falling asleep because of strange feelings in the legs beginning in the evening before sleep. PLMS may cause either sleep-maintenance insomnia (difficulty staying asleep) or a feeling of non-refreshing sleep and daytime sleepiness due to slow, rhythmic limb movements during sleep.”

Tips to Get a Good Night’s Sleep

The first step in managing your sleep problems with type 2 diabetes is to see a doctor or a sleep specialist. Sleep apnea is a serious, potentially life-threatening problem that needs medical attention to remedy. Frequent urination and other sleep-depriving issues should also be treated by a medical professional.

In addition to talking to your doctor and seeing a sleep specialist, here are some additional strategies you can try if you have type 2 diabetes and can’t sleep:

  • Reduce your caffeine intake. Caffeinated beverages can keep you up at night and increase the urge to urinate throughout the night. If you can’t cut caffeine out entirely, Hatipoglu recommends to at least eliminate your intake in the afternoon and evening.
  • Curb the use of electronics in the bedroom. Television is a no-no in the bedroom, as it will keep you up when you need to be focusing on resting. Watch TV in another room, and turn it off at least an hour before you want to nod off. Try reading a book or listening to relaxing music instead.
  • Keep your bedroom cool, dark, and calm. Removing all light from the room, using light-blocking curtains, and outfitting your bed with appropriate bedding helps to create an atmosphere that is conducive to sleep.
  • Create a regular bedtime schedule. Hatipoglu says you need to train your body to get a good night’s sleep. One of the most important ways you can do this is to create a scheduled bedtime and stick to it as closely as possible each night. You can incorporate things into this routine that get your body ready for bed, such as having a few sips of relaxing chamomile tea, meditating, or doing deep breathing exercises before you close your eyes.

Sleep issues are a troubling side effect of type 2 diabetes that can leave you feeling tired all the time. By taking these steps and working with your medical team, you should be able to have sweet dreams every night.

Last Updated: 08/04/2011
This section created and produced exclusively by the editorial staff of EverydayHealth.com. © 2011 EverydayHealth.com; all rights reserved.

Toxins Found in Brand-Name Clothes

Traces of toxic chemicals harmful to the environment and to human health have been detected in products made by 14 top clothing manufacturers, Greenpeace said Tuesday.

Samples of clothing from top brands including Adidas, Uniqlo, Calvin Klein, H&M, Abercrombie & Fitch, Lacoste, Converse, and Ralph Lauren were found to be tainted with the chemicals, known as nonylphenol ethoxylates, the watchdog said at the launch of its report "Dirty Laundry 2."

Greenpeace campaigner Li Yifang said that nonylphenol ethoxylates (NPEs), commonly used as detergents in industries including the production of natural and synthetic textiles, were detected in two-thirds of the samples the group tested.


Read more: Toxins Found in Brand-Name Clothes
Important: At Risk For A Heart Attack? Find Out Now.

Never Fear Cancer Again

"Cancer is an out-of-control epidemic, and conventional treatments don't work," says Raymond Francis, an MIT-trained scientist and chairman of The Project to End Disease. The reason that the "war on cancer" is a failure is that conventional treatments only treat the symptoms and side effects of cancer and not the biological process that causes it in the first place, Francis tells Newsmax Health. He says you can prevent cancer from ever developing in your body to begin with, and he maintains that even if you already have it, you can turn it off — regardless of the type you have — and regain your health.

Story continues below video.


Read more: Never Fear Cancer Again
Important: At Risk For A Heart Attack? Find Out Now.

Bad Economy Pushing Americans to Buy Cheaper Food

Kimberly Reed, executive director of the International Food Information Council Foundation, tells Newsmax that price rather than taste is increasingly becoming a major factor Americans consider when they shop for food.

Reed’s foundation is a Washington-based organization that provides information on food safety, healthy eating, and nutrition.

In an exclusive interview with Newsmax.TV, Reed explained the origins and goals of her group.

“Twenty years ago, we recognized that there was a need for a science-based organization to help consumers, health professionals, and journalists get the facts about food and understand important topics ranging from obesity and energy balance to the latest food safety disaster.


Read more: Bad Economy Pushing Americans to Buy Cheaper Food
Important: At Risk For A Heart Attack? Find Out Now.

New drug could cure nearly any viral infection

Researchers at MIT’s Lincoln Lab have developed technology that may someday cure the common cold, influenza and other ailments.

Wiki image
Anne Trafton
MIT

Most bacterial infections can be treated with antibiotics such as penicillin, discovered decades ago. However, such drugs are useless against viral infections, including influenza, the common cold, and deadly hemorrhagic fevers such as Ebola.

Now, in a development that could transform how viral infections are treated, a team of researchers at MIT’s Lincoln Laboratory has designed a drug that can identify cells that have been infected by any type of virus, then kill those cells to terminate the infection.

In a paper published July 27 in the journal PLoS One, the researchers tested their drug against 15 viruses, and found it was effective against all of them — including rhinoviruses that cause the common cold, H1N1 influenza, a stomach virus, a polio virus, dengue fever and several other types of hemorrhagic fever.

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Colon cleansing: Not so healthy, analysis says

It has been touted as a natural way to improve your heath and cleanse the soul. But doctors are now finding the procedure known as colon cleansing can cause dangerous side effects.

Colon cleansing, technically known as colonic hydrotherapy or colonic irrigation, is a popular treatment, usually performed at spas. It often involves the use of chemicals in the body and in hydrotherapy, the colon is flushed with water through a tube inserted in the rectum.

But oral home remedies are also available and have become popular, especially over the Internet. Now researchers from Georgetown University in Washington, D.C. say there's no evidence any of these colon cleansing treatments work and, in fact, when used improperly can cause cramping, kidney failure and in some extreme cases, death.

"There can be serious consequences for those who engage in colon cleansing whether they have the procedure done at a spa or perform it at home," says the lead author, Dr. Ranit Mishori, a family medicine physician at Georgetown University School of Medicine. "Colon cleansing products in the form of laxatives, teas, powders and capsules... tout benefits that don't exist."

Mayo doctor is no fan of cleanses

Although colon cleansing has been around for centuries as a way to rid the body of unwanted toxins, the American Medical Association determined in the early 1900s that the procedure was invalid; there was no evidence to show the methods worked. And even though there still remains no solid evidence these products do what they claim, colon cleansing has been making a comeback, mainly because manufacturers claim it also helps people lose weight.

"If this method were the key to weight loss, it would be amazing. But there is no evidence that this helps people lose weight,” says Mishori. "Manufacturers don't describe how it works. The statements are a little empty. They say it will enhance your immune system, up your metabolism, give you energy. It’s all pretty vague. Some people swear by it, but it could be a placebo effect. And companies can make these claims, because the federal government doesn't regulate their products."

Not expecting miracles, but I love my cleanses

According to the report released this week in the Journal of Family Practice, Mishori and her colleagues examined 20 studies published in medical literature over the last 10 years.

Investigators noted while these reports showed little evidence of colon cleansing benefits, there were a number of side effects reported following the use of these cleansing methods. Those effects included cramping, bloating, nausea, vomiting, electrolyte imbalance and renal failure. And in some cases, ingredients in these remedies were toxic.

"Some herbal preparations have also been associated with aplastic anemia and liver toxicity," Mishori said.

Researchers also noted that many of the "spas" that offer colon cleansing have no trained clinicians and even organizations such as the National Board for Colon Hydrotherapy and others who promote colon cleansing require technicians who perform professional colon cleansing to have little more than a high school diploma.

"When you flush your colon out with a hose, it's like giving yourself an enema on steroids. You shouldn't put things up there that really don't belong there," stressed Mishori. "Imagine 60 liters of water going through your colon. The stress it puts on the system, and the hose, if not used correctly, could puncture the organ."

As for the home remedies, Mishori says there's no need for them. "We poop and pee for a reason. If you are a healthy person, the body does it for you."

When asked what was the best way to cleanse the body, Mishori was quick to respond.

"Eat a balanced diet, exercise regularly," she stressed, "Get six to eight hours of sleep and see a doctor regularly. But no one wants to do that," she said with exasperation. "But they'll use a hose to flush themselves out! The use of these methods are unhealthy. And what's scary is we only examined the cases that were reported to hospitals and doctors. Imagine all the people who are using these products and methods and have side effects and never go to the hospital. We don't know about them. The numbers could be staggering."

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Childrens Car Seats Contain Chemicals

More than half of children's car seats sold in the United States contain hazardous chemicals, according to a study published Wednesday by a nonprofit environmental group.

Sixty percent of 150 car seats tested by the Michigan-based Ecology Center were found to contain chemicals that can be harmful to human health such as bromine and chlorine, which points to the presence of polyvinyl chlorate (PVC).

Studies in lab animals have found that bromine-containing flame retardants can permanently affect the developing brain, while PVC has been classified by the U.S. Environmental Protection Administration as a known human carcinogen.


Read more: Children�s Car Seats Contain Chemicals
Important: At Risk For A Heart Attack? Find Out Now.

pH Levels and Cancer, Alkaline and Acidic Foods

TruthisTreason.net – Kevin Hayden

The human body is an amazing machine. One of the most important functions of this vessel is its ability to regulate its own acidity levels to a very fine degree. Cells will only function normally within relatively narrow limits of pH. The body regulates its pH by constantly adjusting physiological processes, such as kidney and lung function.

However, the foods you eat can play a role in increasing or decreasing body pH, and some foods can be more alkalizing than others. An acidic body is a magnet for sickness, disease, cancer and aging. Eating more alkaline foods helps shift your body’s pH and oxygenates your system, keeping your body healthy and functioning correctly, preventing cancer, among many other diseases.

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The coming war on vitamins

A consumer walking down the aisle of a local drugstore can choose from a wide variety of supplements, vitamins and nutrients for his or her particular needs. Whether it’s a pill to treat a specific ailment, nutrients and minerals to supplement a deficient diet or vitamins tailored to age and gender to promote long-term health, supplements provide significant benefits to the consumers who rely on them. Yet if Sen. Richard J. Durbin, Illinois Democrat, and the Food and Drug Administration have their way, many of these products will disappear.

Earlier this month, Mr. Durbin and the FDA released proposals for a time-consuming and costly approval process for vitamins and nutritional supplements. The proposals would force companies to pull these products off the shelves for months, if not for good, and significantly raise prices, making the remaining supplements expensive and harder to find. While it isn’t a direct ban, regulatory hurdles such as these are a means by which government bureaucrats get in the way of individuals’ ability to make their own decisions about their health care.

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Consolidation of seed companies leading to corporate domination of world food supply

(NaturalNews) Throughout the history of agriculture across the globe, farming has always been a diversified sector of the economy. Small, self-sustaining, family farms were the order of the day in most cultures. Even as small farms grew larger and more specialized over time, many of them still saved seeds or purchased them from other farmers, which kept control of farming in the hands of the people.

But today everything has changed, as large chemical and agribusiness firms have acquired or merged with seed companies and other agricultural input companies. They have successfully gained a foothold on genetically-modified (GM) crops with transgenic traits.

These primary factors and several others have facilitated a crescendo towards the global domination of agriculture by corporations, and thus the world's food supply.

The dismal state in which we find ourselves today did not come overnight, of course, but it did pick up rapid speed after the introduction of GM crops in the mid-1990s. Since that time, multinational corporations like Monsanto, DuPont, and Syngenta have seized a significant amount of control over the global seed industry, which has greatly limited agricultural diversity and freedom.

The ability to patent both seeds and seed traits has also added injury to insult, as the ability to obtain natural or heirloom seeds is becoming increasingly difficult, and many farmers feel they have no choice but to go with the flow.

Professor Philip H. Howard from the Department of Community, Agriculture, Recreation and Resource Studies at Michigan State University published a study in 2009 entitled Visualizing Consolidation in the Global Seed Industry: 1996 - 2008 that analyzes the trend in agriculture towards corporate dominance.

The report, which was featured in a special issue of the journal Renewable Agriculture, provides both an extensive data analysis of agriculture's dramatic transformation over the past several decades, as well as a highly-informative visual analysis of this truly shocking hostile takeover situation.

Over half of Alzheimer's cases may be preventable, say researchers

Over half of all Alzheimer's disease cases could potentially be prevented through lifestyle changes and treatment or prevention of chronic medical conditions, according to a study led by Deborah Barnes, PhD, a mental health researcher at the San Francisco VA Medical Center.

Analyzing data from studies around the world involving hundreds of thousands of participants, Barnes concluded that worldwide, the biggest modifiable risk factors for Alzheimer's disease are, in descending order of magnitude, low education, smoking, physical inactivity, depression, mid-life hypertension, diabetes and mid-life obesity.

In the United States, Barnes found that the biggest modifiable risk factors are physical inactivity, depression, smoking, mid-life hypertension, mid-life obesity, low education and diabetes.

Together, these risk factors are associated with up to 51 percent of Alzheimer's cases worldwide (17.2 million cases) and up to 54 percent of Alzheimer's cases in the United States (2.9 million cases), according to Barnes.

"What's exciting is that this suggests that some very simple lifestyle changes, such as increasing physical activity and quitting smoking, could have a tremendous impact on preventing Alzheimer's and other dementias in the United States and worldwide," said Barnes, who is also an associate professor of psychiatry at the University of California, San Francisco.

The study results were presented at the 2011 meeting of the Alzheimer's Association International Conference on Alzheimer's Disease in Paris, France, and published online on July 19, 2011 in Lancet Neurology.

Barnes cautioned that her conclusions are based on the assumption that there is a causal association between each risk factor and Alzheimer's disease. "We are assuming that when you change the risk factor, then you change the risk," Barnes said. "What we need to do now is figure out whether that assumption is correct."

Senior investigator Kristine Yaffe, MD, chief of geriatric psychiatry at SFVAMC, noted that the number of people with Alzheimer's disease is expected to triple over the next 40 years. "It would be extremely significant if we could find out how to prevent even some of those cases," said Yaffe, who is also a professor of psychiatry, neurology and epidemiology at UCSF.

###

The research was supported by funds from the Alzheimer's Association, the National Alliance for Research on Schizophrenia and Depression, the UCSF School of Medicine and the National Institute on Aging.

SFVAMC has the largest medical research program in the national VA system, with more than 200 research scientists, all of whom are faculty members at UCSF.

UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.

What's in Your Meat?

The Agriculture Department wants consumers to know when there's less chicken in their chicken.

A proposed rule aimed at food companies would require that poultry and other raw meats be labeled appropriately when they're plumped up by added solutions such as chicken broth, teriyaki sauce, salt, or water. The practice of adding those ingredients is common, but many consumers don't know about it.

According to USDA, about one-third of poultry, 15 percent of beef, and 90 percent of pork may have added ingredients — about 40 percent of all raw, whole cuts of meat. The rule does not apply to ground beef, which may have other added substances.


Read more: What's in Your Meat? USDA Calls for Clearer Labeling
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Dr. Brownstein: 5 Lifestyle Changes for Prostate Health

Prostate cancer is a concern for most men, and with good reason — more than 190,000 new cases are diagnosed each year in the United States, according the American Cancer Society. But there are steps men can take to keep their prostate gland healthy, and try and minimize cancer risk, Newsmax Health contributor Dr. David Brownstein says.

“Unfortunately, most men are susceptible to (prostate cancer),” says Brownstein, editor of “The Natural Way to Health” newsletter. “We have one in three men in the United States with prostate cancer today. It’s occurring at epidemic rates. It generally occurs in older men, but lately we’re seeing younger and younger men being afflicted with this.”

Story continues...Read more: Dr. Brownstein: 5 Lifestyle Changes for Prostate Health

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Is Robotics Driving Prostate Surgeries?

After Wisconsin hospitals acquired robotic surgery technology, the number of prostate removals they performed doubled within three months, a new study shows.

By contrast, the number of prostate surgeries stayed the same at hospitals that didn't purchase the new $2 million technology.

The increase in such surgeries raises questions about whether more doctors at hospitals with robots are recommending surgery for men with prostate cancer, say the authors, instead of alternative treatments like radiation or "watchful waiting."


Read more: Is Robotics Driving Prostate Surgeries?
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How To Appeal A Health Insurance Denial

Getting your health insurance claim denied can feel like insult added to injury, but if you take these steps you can get your claim "rehabbed," and get your money.

The NY Times Bucks blog interviewed Martin Rosen, whose business, Health Advocate, helps employees negotiate the tricky waters of their employer insurance. He offered these tips:

1. Double-check all the rules of your insurer's appeals process, especially deadlines.
2. Get all your documents ready and organized.
3. Call HR if you get insurance through your employer. They might become your advocate.
4. Ask your doc to write a "letter of medical necessity" and send it to the insurance company.
5. Make a log of all your calls when you contact the insurance company, including dates, times, whom you spoke to, what you talked about, and the length of the conversation.
6. Write down and refine your logical argument for why your claim should go through and refer to it when necessary throughout the process.
7. Keep checking on the status of your claim with the insurance company.

Have you ever had to dispute a health insurance denial? What methods did you use?

7 Steps in Appealing a Health Insurance Denial [bucks.blogs.nytimes]

From ConsumerReports.org:

Teflon Chemical Linked to Arthritis

High blood levels of a man-made chemical used in non-stick coatings were associated with a raised risk of arthritis in a large new study of adults exposed to tainted drinking water.

Researchers found that people with the highest levels of perfluorooctanoate (PFOA) in their blood were up to 40 percent more likely to develop arthritis than people with lower blood levels more typical of the general U.S. population.

Dr. Kim Innes of the School of Medicine at West Virginia University and colleagues used data on nearly 50,000 adults living in areas of Ohio and West Virginia where a chemical plant had contaminated water supplies with PFOA and perfluorooctane sulfonate (PFOS), both chemicals widely used in non-stick and stain-resistant coatings.


Read more: Teflon Chemical Linked to Arthritis
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Nanotechnology: Tracking food from farm to fork…and you right along with it

image source
Marti Oakley, Contributing Writer
Activist Post

I had come across an article in the Dairy Reporter last year, about the coming plans to insert nano-technology into food. In the article from DR: Nanotechnology in food: What’s the big idea? By Caroline Scott-Thomas, 26-Jul-2010 this observation was made:

“At IFT’s nanoscience conference last week, major industry players discussed how to avoid a rerun of the GMO debacle with consumers – with some saying that one solution could be to say nothing about introducing nanotechnology in foods and to do it anyway.”

We all have enough experience with today’s bio-pirates who are openly colluding with the USDA, FDA and anyone else in government, like “Dirty Harry” Reid NV (D), who single-handedly and unanimously cast the one vote needed to pass the fake food safety bill, to know that food safety and longer shelf life is most likely not what this technology is actually intended to do. As it is, most products on the shelves of stores now are so chemically laden and contain so much GMO that I doubt spoilage is an option. After all…can chemicals, pesticides and herbicides actually rot?

Most of what sits in our stores is not really food as we have known it. It is a stew of sorts; chemicals, additives, flavorings, colorings, enhancers, preservatives, aspartame, neotame, and stuff we can’t even identify along with residual hormones, vaccines, antibiotics, herbicides and pesticides. It has been irradiated, sprayed with viruses and now covered in ammonia. Reading any label for content makes one think you would be just as well off if you drank floor cleaner and it most likely might be a lot tastier although just as empty of nutrition.

Type 2 diabetes in newly diagnosed 'can be reversed'

An extreme eight-week diet of 600 calories a day can reverse Type 2 diabetes in people newly diagnosed with the disease, says a Diabetologia study.

Newcastle University researchers found the low-calorie diet reduced fat levels in the pancreas and liver, which helped insulin production return to normal.

Seven out of 11 people studied were free of diabetes three months later, say findings published in the journal. Read More>>>>

Mother's milk: A secret weapon for everything

Motherhood in the FatherlandPhoto: DPA

Mother's milk: A secret weapon for everything

Yes, to cure all that ails that tiny tummy (and other mini body parts), mum's boobs have the answer.

To say that nursing is encouraged here in the Fatherland would be an understatement. Even the makers of formula acknowledge on their packaging that, “Breastfeeding is the best way to feed your baby.”

There is even the government-funded German National Breastfeeding Institute (Nationale Stillkommission) whose responsibility is to ensure that all mothers have the facts and resources they need to successfully breastfeed.

Could you imagine if US First Lady Michelle Obama tried to implement something like that in America? She had enough troubles merely promoting the idea of breastfeeding. So many US blogs I read often talk about breastfeeding, but always with the caveat that “breastfeeding is the best choice for me and my family.”

But in Germany I have learned that breast milk cures more than just baby hunger. Six months in, I wouldn’t be surprised if I were told my chest contained the proverbial fountain of youth.

As Luisa went through her first growth spurt, she went through her first gas pains. Not to worry, my midwife said, and told me to offer her the breast. As the milk goes through her system, it would literally push the gas out the other end. Breastfeeding also relieves me of worrying about Luisa’s, ahem, “output”. As long as she was solely breastfed, anything was normal and I wasn’t to worry about it.

At four weeks, Luisa came down with a case of baby acne. I wasn’t about to swab her face with Clearasil, but I was concerned about this pile of bumps appearing on her smooth cheeks. What does my midwife recommend? Simply use Muttermilch as a cream and dab it on the worst spots as often as I liked. I’m not actually sure if it was the breast milk, but the acne cleared up within a week.

Breast milk also has healing properties. “Toe-curling pain,” was what one friend warned me to expect during the first 10 days of baby latching on to very sensitive spots to nurse. And as my nipples cracked, my toes curled.

But as we left the hospital, a doctor had reminded me that breast milk was an excellent nipple cream and “it’s safe for baby too,” she said with a smile.

Canadian Sara Read even discovered that breast milk could help with a stubborn umbilical chord. “My midwife told me to apply breast milk to Annika’s umbilical chord stub to help it come off,” she said, adding that she was sceptical at first.

“I only did it half-heartedly and when it wasn’t gone after a couple weeks, my midwife grabbed my boob, squeezed out some milk onto a q-tip, applied it to the umbilical stub and — pop! — within a matter of seconds she had worked it off with the milk-soaked swab.”

English mum Rachel Fox was told breast milk would help clear up her eldest child’s gooey eye.

“He had a sticky eye infection and [the midwife] had us squirting breast milk directly into his poorly eye," she told me. "I was quite shocked initially, but it did the trick. A few days later the infection was gone. Not a chemist in sight!”

Not just eyes, but ear infections can also be cured with a good squirt of the white stuff. In fact, breast milk is a great substitute for antibiotic ointment. Cuts and scrapes heal much faster with a little bit of Muttermilch applied to them. And when a baby’s sensitive bum goes red, there is no need to reach for creams with all sorts of chemicals; just rub on some breast milk, allow to air dry and carry on.

Adults with scrapes, cuts, burns, dry skin, acne and cold sores can also benefit from the application of breast milk. Allegedly warts, insect bites, chicken pox and eczema too.

But back to Luisa’s runny nose. I’ve used my Muttermilch many times to clear up her little nose. While it’s effective, there is one problem: The application. I’ll leave you to think about the mechanics.

http://www.thelocal.de/lifestyle/20110708-36147.html

Low Testosterone Associated With Obesity and the Metabolic Syndrome Contributes to Sexual Dysfunction and Cardiovascular Disease Risk in Men With Type

  1. Christina Wang, MD1⇓,
  2. Graham Jackson, MD2,
  3. T. Hugh Jones, MD3,
  4. Alvin M. Matsumoto, MD4,
  5. Ajay Nehra, MD5,
  6. Michael A. Perelman, PHD6,
  7. Ronald S. Swerdloff, MD1,
  8. Abdul Traish, PHD7,
  9. Michael Zitzmann, MD8 and
  10. Glenn Cunningham, MD9

+ Author Affiliations

  1. 1Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California
  2. 2London Bridge Hospital, London, U.K.
  3. 3Robert Hague Centre for Diabetes and Endocrinology, Barnsley Hospital, and the Department of Metabolism, University of Sheffield Medical School, Sheffield, U.K.
  4. 4Geriatric Research, Education and Clinical Center, V.A. Puget Sound Health Care System, Department of Medicine, University of Washington School of Medicine, Seattle, Washington
  5. 5Department of Urology, Mayo Clinic, Rochester, Minnesota
  6. 6Departments of Psychiatry, Reproductive Medicine, and Urology, NY Weill Cornell College of Medicine, New York, New York
  7. 7Department of Urology, Boston University School of Medicine, Boston, Massachusetts
  8. 8Clinical Andrology/Centre for Reproductive Medicine and Andrology, University Clinics of Muenster, Muenster, Germany
  9. 9Departments of Medicine and Molecular and Cellular Biology, Baylor College of Medicine, St. Luke’s–Baylor Diabetes Program, Houston, Texas
  1. Corresponding author: Christina Wang, wang@labiomed.org.

Men with obesity, the metabolic syndrome, and type 2 diabetes have low total and free testosterone and low sex hormone–binding globulin (SHBG). Conversely, the presence of low testosterone and/or SHBG predicts the development of metabolic syndrome and type 2 diabetes. Visceral adiposity present in men with low testosterone, the metabolic syndrome, and/or type 2 diabetes acts through proinflammatory factors. These inflammatory markers contribute to vascular endothelial dysfunction with adverse sequelae such as increased cardiovascular disease (CVD) risk and erectile dysfunction. This review focuses on the multidirectional impact of low testosterone associated with obesity and the metabolic syndrome and its effects on erectile dysfunction and CVD risk in men with type 2 diabetes. Whenever possible in this review, we will cite recent reports (after 2005) and meta-analyses.

Epidemiological studies of low testosterone, obesity, metabolic status, and erectile dysfunction

Epidemiological studies support a bidirectional relationship between serum testosterone and obesity as well as between testosterone and the metabolic syndrome. Low serum total testosterone predicts the development of central obesity and accumulation of intra-abdominal fat ( 1 3). Also, low total and free testosterone and SHBG levels are associated with an increased risk of developing the metabolic syndrome, independent of age and obesity ( 1 3). Lowering serum T levels in older men with prostate cancer treated with androgen deprivation therapy increases body fat mass ( 4). Conversely, high BMI, central adiposity, and the metabolic syndrome are associated with and predict low serum total and to a lesser extent free testosterone and SHBG levels ( 1 3, 5). Because obesity suppresses SHBG and as a result total testosterone concentrations, alterations in SHBG confound the relationship between testosterone and obesity.

Low total testosterone or SHBG levels are associated with type 2 diabetes, independent of age, race, obesity, and criteria for diagnosis of diabetes ( 6, 7). In longitudinal studies, low serum total and free testosterone …