The future of cancer treatment — hailed as the “holy grail” of early detection — is now being put to the test.
Following a radically successful trial on cancer patients, a new blood test that promises to predict tumors more than a year before they begin to form is now being applied in hospitals across the United Kingdom.
“This is the first pan-cancer blood test,” said Ashish Tripathi, founder and CEO of Tzar Labs as well as chairman of Epigeneres Biotech, the Indian firm where the test was first developed in 2021. An updated report on their findings was published this month in the journal Stem Cells.
“We can detect [cancer] earlier than other known technologies … before the tumor has physically formed,” Tripathi continued during a new interview with author and medical advocate Deepak Chopra.
“Not only can I actually detect it at this stage — I can actually tell you which cancer and where it is forming, straight from a blood test.”
In a trial of 1,000 participants — 500 non-cancer and 500 cancer patients — researchers were able to accurately anticipate the formation of tumors across at least 25 types of cancer, including all of the most prevalent and deadly varieties, such as breast, pancreatic, lung and colorectal. Even some participants within the presumed “non-cancer” group were found to have a predisposition for future cancer diagnosis.
“We did not get even one false negative, not even one false positive,” Tripathi noted.
Hospitals in the UK have already begun to implement the new technique for further proof of concept, while researchers hope to take it to the United States soon.
Dr. Sherif Raouf, a gastrointestinal cancer specialist who will lead a trial at St. Bartholomew’s Hospital in London, said, “Picking up cancer at the earliest stage is the holy grail of cancer medicine.”
“Normally this is not an easy process. Many patients currently undergo scans, biopsies and clinic appointments. To have one blood test to detect the presence of cancer at the earliest stage — or even before it develops — could save many lives. This could be a game-changer.”
Despite the numerous blood-based cancer screening methods that have recently been in development, Tripathi’s team’s approach differs by zeroing in on stem cells with a biomarker for cancer, as opposed to searching for full-blown tumor cells that may already be present. This allows them to determine whether cancer is on the horizon well before those cells have progressed to form a tumor.
All cells, good or bad, begin as stem cells, and those that go on to form tumors possess genetic markers that prompt them to do so.
It takes 1 billion cancer cells to form a tumor that measures just 1 cubic centimeter — a very small mass to detect even for CT scanners. But inside the body, that initial tumor is shedding cancerous cells as it grows, which enter the bloodstream and begin seeding for new tumors, or metastasizing, in various other organs.
Most of the previously developed blood tests for cancer diagnosis were made to find fully fledged tumor cells traveling through the blood. This method is prone to false negatives, according to Tripathi, because not every sample of blood will turn up those particular cells.
“Here lies the breakthrough that we’ve made: Every liquid biopsy company that you’re aware of … they were looking for these [tumor cell] fragments in peripheral blood,” Tripathi explained. Unfortunately, “very few” tumor cells are circulating in the early stages of cancer.
And by Stages 3 or 4, when cancer cells have proliferated throughout the bloodstream, enough to be detected by conventional means, it’s often already too late for treatment.
The new “prognostic” test not only sees cancer at Stages 1 or 2 but also knows whether a patient’s stem cells are fated to become cancerous well before the first stage — up to 18 months ahead. This gives doctors a huge advantage in terms of targeted treatments to prevent the formation of tumors.
It’s good news for those who have already been diagnosed with cancer too. Whereas traditional tissue biopsies may help determine whether or not a tumor is metastatic, the new blood test can say exactly which organ(s) the would-be tumor cells will target, noninvasively and well before the first tumor has amassed.
It is best to avoid getting bitten by a mosquito and here is why...getting bitten by a mosquito could result in a great deal of health issues and even death. Let's look at what happens when you get bitten by a mosquito!
By Jennifer Rae Vliet
What Happens To Your Body When It's Bitten By A Mosquito
BY JOEY KEOGH from TheList.com Mosquitoes must find nothing more delicious than human skin. That's how it feels when you're covered in itchy bites, agonizing over how to avoid scratching. So what really happens when these deadly insects bite us?
The female mosquito lands on your skin and extends her proboscis (a narrow part of the mouth used to retrieve blood) into it as she tries to locate a yummy blood vessel. Mosquitoes aren't teeny vampires, though, they just need protein-rich blood to produce eggs and propagate their species.
The mosquito injects us with a vasodilator, which keeps blood flowing rather than clotting while it feeds. It is this injection of the mosquito's saliva that causes the problem. As Dr. Renee Matthews, MD notes, our body reacts pretty strongly to this. "When a mosquito bites us, our body's immune system creates histamines, causing the skin around the mosquito bite to itch," she advises. Still, you might not notice right away and may even start itching hours later. Likewise, "Redness and swelling are part of the immune reaction, as well."
The Purpose for Mosquitos according to ThoughtCo.com in a column on The Most Interesting Facts About Mosquitos
Why Do Mosquitoes Exist?
Basically, mosquitoes exist because they're next to impossible to wipe out. Species don't exist in a vacuum; as long as they can find food and don't have environmental pressure against them, they'll continue. Mosquitoes are millions of years old as a species. In the ecosystem, they do serve as food for other species (birds, frogs, and fish) and as pollinators. The larvae eat detritus in the water, helping to clean it. There are more than 3,000 species of mosquitoes, but only about 200 bite humans.
So, whats the big deal? Dr. Josh Axe reports that you can actually acquire parasites from a mosquito bite...
How does someone become infected with a parasite?
Believe it or not, a relatively high percentage of adults living in the United States may carry parasites. Where and how does somebody get infected with a parasite?
Parasites are generally acquired from consuming contaminated food or water, but people with imbalanced gut flora, leaky gut syndrome or a weakened immune system may be more susceptible. Some can also be spread through the bite of a mosquito or sand fly, or transmitted to humans from animals such as cows and pigs that are infected with parasites like Cryptosporidium or Trichinella. (SOURCE)
Look what is happening right now in Peru
Brimful clinics, cemeteries as dengue ravages Peru
Piura (Peru) (AFP) – Two months after cyclonic downpours flooded the town of Catacaos in northern Peru, dozens of inhabitants lie sick and dying of dengue, a disease carried by mosquitos attracted by stagnant water.
Near the border with Ecuador, Peru's Piura region is battling a new health crisis even as the South American country is still recovering from the world's highest reported Covid-19 death rate.
This time it is an epidemic of dengue, a viral disease with symptoms ranging from fever, headache and joint pain to bleeding, organ failure and sometimes, death.
The virus is carried by the Aedes aegypti mosquito that lays its eggs in standing water, of which there is a lot in Piura since cyclone Yaku hit northern Peru in March.
Dozens of people were killed and thousands affected as rivers burst their banks, destroying homes and infrastructure.
Half of the Piura region's 416 clinics were damaged by the cyclone that also paralyzed the local economy as thousands lost their ability to survive from informal jobs.
By June 13, Piura had reported 82 dengue deaths -- including 11 children -- and more than 44,000 infections since the start of 2023, said the region's rights ombudsman Cesar Orrego.
This was about a third of the national toll of 248 deaths and more than 146,000 infections.
We have lost control" of the epidemic, vector-borne diseases expert Valerie Paz-Soldan of the Cayetano Heredia University in Lima told AFP.
On Thursday, Peru's health minister resigned over her handling of the crisis.
Most of Piura's 1.8 million inhabitants live along the coast.
In Catacaos, an agricultural area, Yaku turned roads into rivers, destroyed the drinking water and sewerage systems, and ruined mango, grape and rice crops.
Water accumulated in open tanks, hollows and containers, multiplying mosquito breeding grounds. In the heart of Catacaos, the football field is still water-logged.
Multiple fumigation efforts failed to stop the epidemic spreading like wild-fire through the town's rickety homes. (SOURCE)
Then we have the Gates meddling in on nature and we know how things go when The Gates' viewpoint on sustaining life goes...this in its best estimation may sound good to environmentalists but the lack of trust with anything "Bill Gates" related needs to be heavily noted here.
A Company Just Released 150K Genetically Modified Mosquitoes in the United States
Genetically modified mosquitoes were just released in the US for the first time, thanks to a biotech firm funded by Bill Gates.
he Bill Gates-backed biotech firm Oxitec is going ahead with plans to release hundreds of millions of gene-altered mosquitos in Florida in order to test an experimental new form of population control, the company confirmed in a press release. The initial batch of mosquitoes was released this week.
The controversial project, conducted as part of a partnership between the Florida Keys Mosquito Control District (FKMCD) and Oxitec, will see six locations in the region host Oxitec’s gene-hacked male Aedes aegypti mosquitos over the next few months.
Oxitec — which announced a collaboration with the Bill & Melinda Gates Foundation in 2018 — says the new tests could help to greatly reduce populations of the mosquito breed, which is responsible for spreading diseases such as dengue and malaria.
As Oxitec emphasizes in its press statement, the company's mosquitos are male and, therefore, do not bite.
Instead, they are intended to reduce the number of potentially disease-transmitting female Aedes aegypti by introducing a self-limiting gene that sees offspring die before reaching adulthood.
The firm says the Aedes aegypti accounts for only 4 percent of the mosquito population in the Florida Keys, but is responsible for almost all disease transmission. The company also states that community support for the project is "high."
Controversy amid global plans to gene-hack mosquitos
Still, the method is controversial due to the fact that a genetically altered species is being released into an ecosystem with potentially unknown consequences. Critics have also pointed to the fact that this may open doors for firms to use gene-altered invasive species for other uncontrolled projects.
Oxitec faced a backlash in August 2020, when it originally released its Florida Keys plans. In a press statement at the time, Dana Perls, the food and technology Program Manager at Friends of the Earth, said that "the release of genetically engineered mosquitoes will needlessly put Floridians, the environment and endangered species at risk in the midst of a pandemic."
The Oxitec technology has already been tested in São Paulo, Brazil, where after 13 weeks, it suppressed up to 95 percent of the mosquito species.
Oxitec's isn't the only method for gene-altering mosquitos to curb their populations — this month, it was announced that researchers from Imperial College London have successfully altered the gut genes of mosquitos to spread antimalarial genes to their offspring. The same team had previously used the gene-editing tool CRISPR to eradicate a population of Anopheles gambiae in a lab. (SOURCE)
Mosquitos are something to avoid and something to respect all at the same time. I personally do what I need to do to keep from being bitten by them and if I happen to get the unfortunate bite, I always have The Bug Bite Thing tool at the ready. This is not a paid sponsorship but worth the mention because this little tool can help reverse what the mosquito deposits into your skin if you can get to it asap.
God had a purpose for all of His creations and expects us to be good stewards of our land and all that He has given us dominion over. There is a way to protect human life first and foremost and we are so advanced that all's it takes is research on ways to handle the problems that mosquitos can cause. When you look around and gene altering endeavors, it is imperative to look ahead and see how that is going to affect the cycle of life for other species but once again, human life is a priority and as you can clearly see, things can get out of hand and very quickly. The liberal agenda and their displaced compassion to a large degree and an outright mission to punish those of us that want to put humans first. They do not want us to harm life and protect even the flea; and by doing so, they have really tilted the scale and have caused a lot of harm to humankind.
In 2011, the state of California banned the usage of an incredibly effective enzymatic treatment of 2-{1-Methyl-2-(4-phenoxphenoxy) ethoxy} pyridine. By doing so, they actually caused what exterminators were calling a SUPER FLEA. They cared more about the fleas then everybody and every other living thing instead. By not being allowed to control the flea population, animals suffered GREATLY and thus as a result, PEOPLE SUFFERED. Exterminators were using their strongest chemicals and still couldn't control the problem. Outside critters suffered, birds, racoons, squirrels, you name it. FINALLY, they allowed the product back into the state in 2017. It was A LONG 6 years, let me tell you!
The bottom line is, get educated, protect yourself, and let's fight for life and be good stewards with what God has given to us, use our noggins and do what needs to be done as God would see fit!
Senate Homeland Security and Governmental Affairs Committee Chairman Rand Paul(R-KY) will be asking theJusticeDepartment to open an investigation into Dr.Anthony Fauci’s executive assistant for the alleged destruction of records related to the origins ofCOVID-19.
Paul announced Wednesday that he and fellow Republicans would be pursuing a DOJ referral for Fauci’s assistant after failing to secure enough votes from Democrats on the panel to request a court order granting her immunity to share information about Fauci’s alleged illegal activity.
An Arizona man who was diagnosed with Parkinson's Disease has figured out how to halt and reverse the symptoms, but discovered that no one seems to care. Hans Bogensberger, an 82-year-old retired nuclear physicist from Sun City, believes the principles of quantum physics explain what happened and would like to share how he did it with others suffering from the disease.
He didn't just stop the disease from progressing, but he reversed the symptoms. The hair on the top of his head has started growing back. He now competes in fencing and is the fencing champion for his age group in Arizona.
Parkinson's occurs when the body doesn't produce enough dopamine, destroying or disabling brain cells and neurons. This results in tremors, loss of balance, hallucinations, loss of memories and more. Until now, Parkinson's could not be stopped, only slowed.
Bogensberger developed Parkinson's in his late 60s or early 70s, and it progressed to the stage where he could hardly walk. He lost his long and short-term memory, and could no longer create poetry or remember geography and science.
Two or three years ago, entering his 80s and feeling miserable with all of the symptoms, Bogensberger felt like returning to the sport of saber fencing, which he played when he was 13 to 14 years old. It was one of a few simple things his brain could easily remember. He could barely stand up to do it.
Maybe there is a reason GOD FORBIDS EATING UNCLEAN ANIMALS!
A multi-state outbreak of a dangerous liver disease is being investigated by officials after more than three dozen people have been sickened.
The Centers for Disease Control and Prevention (CDC) is investigating an outbreak of hepatitis A across four states. Thirty-seven people have been sickened and 30 have been hospitalized. No deaths have been reported.
Short brisk walks can match the health benefits of higher daily step goals, a new study suggests. Iuliia Burmistrova/ Moment/ Getty Images
Higher daily step counts have long been linked to a lower risk of premature death, but not everyone has the time or capacity to walk a lot every day.
Now, a study has found that increasing walking speed may be just as effective as increasing step count in lowering the risk of both all-cause and cardiovascular deaths.
The research found that people who achieved fewer than 5,000 steps per day at a rapid pace had a mortality risk similar to that of those who did 10,000 steps per day at a slower pace.
The researchers suggest that even if you cannot achieve a high daily step target, walking regularly and speeding up your pace when you do walk could have similar benefits.
Although the 10,000 steps a day recommendation has been widely acknowledged as an arbitrary number, experts agree that walking more is good for your health and may decrease your risk of premature death.
Ever wonder why certain medications are called "wonder drugs"?
Sometimes it's because of the tremendous health benefits the drug provides for a particular condition, like insulin for type 1 diabetes or antibiotics for pneumonia. Or, it might be because the drug is good for many different conditions: aspirin has often been called a wonder drug because it can relieve pain, treat or prevent cardiovascular disease, and even prevent cancer.
Could metformin be joining this list? It's approved in the US to treat type 2 diabetes when used with diet and exercise by people ages 10 and older. But in recent years, interest has grown regarding its potential to prevent or treat a variety of other conditions, including aging. Yes, aging. If that's true, "wonder drug" might be an understatement.
Among foods that inspire a cult-like following, pork often leads the pack, as evidenced by the65% of Americanseager to name bacon the country’s national food.
Unfortunately, that popularity comes at a cost. Along with being the most commonly consumed meat in the world, pork may also be one of the most dangerous, carrying some important and under-discussed risks that any consumer should be aware of (1).
A review of participant health insurance records revealed that, compared to participants in the lowest performance category, those with the highest scores had a lower risk of death from any cause over the median seven-year follow-up.
High scores in balance and agility, lower-body strength, and cardiorespiratory fitness were associated with the greatest reduction in mortality risk.
That’s likely because balance, agility, and strength play a “central role” in fall prevention and injury avoidance, said Milica McDowell, MS, DPT, C-EP, a physical therapist and exercise physiologist who was not involved with the study.
Falls are the leading cause of injury among adults ages 65 and older, and the risk of dying from a fall increases with age.
Did you know that the vast majority of the world’s meat consumption (excluding fish) comes from just five animals? Yet the one that tops the list is also the only one the Bible expressly forbids: pork. Many are familiar with this fact, but few understand the reason—and the wisdom behind it.
According to the Food and Agriculture Organization of the United Nations (FAO), meat from pigs, chickens, cows, sheep, and goats accounts for approximately 98 percent of all the meat eaten in the world. Recent FAO reports show that pork makes up the largest share at 36 percent, followed by chicken (33 percent), beef (24 percent), and goat and mutton (5 percent). Many think the Bible’s prohibition against people eating pork is quaint, a tradition, maybe even a superstition, but the real truth is quite practical—and serves to highlight God’s understanding of His own creation and His concern for the wellbeing and health of mankind.
So, let’s take a look at some medical research that provides evidence of the potential health risks related to pork consumption and how this supports the Bible’s dietary instruction regarding pigs.
A significant number of men who undergo prostatic artery embolization (PAE) as their first procedure for benign prostatic hyperplasia (BPH) may eventually require reintervention.
A new paper in the Journal of Vascular and Interventional Radiology describes reintervention rates of men with BPH in the years following PAE. According to the data, as many as 25% of these men will require additional treatment within five years of their first intervention. The new data provide valuable insight into outcomes that are not yet well described, authors of the paper contend.
“Published reintervention estimates after PAE have ranged from approximately 16%–51% at 40 years; this wide range reflects differing endpoint definitions (for example, whether medical treatment, repeat PAE, or specific surgical modalities are counted) as well as potential differences in durability, and derive predominantly from single-center series or international registries with limited generalizability to U.S. practice patterns,” writes Tarub S. Mabud MD, MSc, with the division of vascular and interventional radiology at Columbia University Irving Medical Center in New York. “The durability of PAE in routine U.S. practice, outside of high-volume academic centers and protocolized trials, remains less well characterized.”
PAE symptoms related to benign prostatic hyperplasia are present in about one in four men by age 55, and in half of 75-year-old men.
Treatment is only necessary if symptoms become bothersome.
The PAE procedure has a lower risk of urinary incontinence and sexual side effects (retrograde ejaculation or erectile dysfunction), when compared with more invasive surgical procedures such as a transurethral resection of the prostate (TURP).
Protein is necessary to build and sustain muscles. This includes skeletal muscles, the muscles that allow your heart to beat and the muscles that open up your airways to breathe
Grocery shelves today are filled with protein-enriched cereal, pasta, chips, pretzels, coffee, bread and even protein-fortified Pop-Tarts.
When a breakfast pastry known mainly for sweetness and convenience is marketed as a protein source, it is clear that food companies are capitalizing on consumers' growing interest in protein.
A team at the University ofChicagoMedicine Transplant Institute has updated the results of the ongoing clinical trial of patients with type 1 diabetes.
Unlike type 2 diabetes, which typically comes on later in life and is caused by lifestyle factors such as obesity, type 1 diabetes, which affects as many as 4 million Americans, is an unpreventable autoimmune disorder in which the immune system destroys insulin-producing cells in the pancreas.
Without insulin, type 1 diabetics' bodies have no way to regulate blood sugar, which can build up in the bloodstream and skyrocket. Instead, their bodies break down fat for fuel, creating acidic byproducts called ketones and eventually cause diabetic ketoacidosis (DKA), leading to brain swelling, kidney failure, cardiac arrest and potential death.
In the trial, 10 type 1 diabetics underwent transplantation of islet cells, tiny clusters of specialized cells scattered throughout the pancreas that produce hormones to regulate blood sugar.
After just four weeks, all 10 achieved insulin independence, meaning their bodies were able to produce insulin on their own without costly supplemental injections.
Their A1C, which measures the amount of glucose in the blood, also fell from eight percent on average, which indicates diabetes, to 5.3 percent, which is considered non-diabetic.
