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Fatty Liver Disease – Exciting Announcement from Eli Lilly

Eli Lilly announced promising findings from a midstage trial indicating that tirzepatide, a widely-used medication for weight loss and diabetes, may also serve as an effective treatment for fatty liver disease. The study results unveiled additional potential health benefits of tirzepatide, beyond its established roles in weight management and blood sugar control under the brand names Zepbound and Mounjaro.

The pharmaceutical giant disclosed that tirzepatide demonstrated success in a phase two trial targeting metabolic dysfunction-associated steatohepatitis (MASH), a severe form of liver disease. MASH, characterized by liver fat accumulation and inflammation leading to fibrosis, currently lacks direct treatment options. Studies suggest that approximately 3% to 5% of adults in the U.S. suffer from MASH. Unfortunately MASH is growing with no end in sight.

The trial, involving around 190 adults with advanced stages of liver scarring due to MASH, showed positive outcomes across all dose levels of tirzepatide. Notably, the medication met its primary objective by aiding patients in achieving freedom from MASH without worsening liver scarring compared to those not receiving treatment. For instance, approximately 74% of patients receiving the highest tirzepatide dose remained MASH-free with stable liver scarring after a year, in contrast to around 13% of those on a placebo. Now that is a huge difference.

While the extent of liver scarring reduction wasn’t explicitly disclosed, Eli Lilly highlighted the drug’s clinically meaningful impact across various dosage strengths. The company’s Chief Scientific Officer expressed equal enthusiasm regarding tirzepatide’s potential in reducing liver scarring, emphasizing the absence of concerning data hindering advancement to phase three trials.

Regarding safety, adverse events associated with tirzepatide aligned with prior studies in patients with obesity and diabetes. Typical side effects reported in previous trials of Zepbound included diarrhea, nausea, and vomiting.

Eli Lilly intends to unveil comprehensive findings from the phase two trial at an upcoming medical conference, signifying a significant step forward in exploring tirzepatide’s therapeutic potential beyond its established uses.

During my career, I’ve had the privilege of witnessing the cure for Hepatitis C. It is my sincere hope and fervent prayer that we can achieve similar breakthroughs for metabolic dysfunction-associated steatohepatitis (MASH), commonly known as Fatty Liver Disease.

Colloidal silver a powerful remedy against superbugs, study finds

“When combined with a small amount of silver nanoparticles, the amount of antibiotic needed to inhibit the bacteria decreased 22-fold, which tells us that the nanoparticles make the drug much more potent,” Czy? explained.

(Natural News) by Ethan Huff

(Natural News) Researchers at the University of Florida have discovered that silver nanoparticles, also known as colloidal silver, can serve as a powerful remedy against antibiotic-resistant bacteria, more commonly known as “superbugs.”

Certain hard-to-fight infections die on contact with silver, the scientists revealed in their paper, which was published in the journal Frontiers in Microbiology. The antimicrobial properties of silver nanoparticles, or microscopic spheres of silver small enough to operate at the cellular level, could aid in the fight against antibiotic-resistant infections, which kill more than a million people globally every single year.

The purpose of the study was to test the efficacy of silver nanoparticles alongside a common class of broad-spectrum antibiotics known as aminoglycosides. Daniel Czy?, the study’s senior author, told the media that his team’s experiments show that the two things do, in fact, work synergistically.

Taking aminoglycosides by themselves at prescribed doses is risky, carrying with it the potential for deadly side effects. Adding silver into the mix allows for lower doses of aminoglycosides to be taken with amplified effect, making for a safer remedy.

Autumn Dove, another study author, explained that prolonged overuse of antibiotics has created an environment where traditional remedies no longer work, hence the need for alternative remedies that include the addition of silver.

“Let’s say you get a bad burn on your hand, and it gets infected with one of these resistant strains of bacteria,” Dove is quoted as saying. (Related: Copper is another healing metal with strong efficacy against superbugs.)

“It’s possible that dressing that burn with a combination of silver nanoparticles and antibiotics could both clear that infection and prevent those resistant bacteria from spreading elsewhere.”

Low-dose antibiotics combined with silver a better remedy than antibiotics alone

While antibiotics primarily target bacteria, they are also known to damage human and animal cells. This makes them problematic even for their approved use, which is killing people’s healthy gut bacteria along with the bad kind.

The great thing about silver is that, as confirmed in tests using a microscopic worm called C. elegans, it does not harm non-bacterial cells like antibiotics do. Silver selectively targets just the harmful bacterial cells, making it a better remedy alongside lower doses of antibiotics as opposed to just higher doses of antibiotics by themselves.

The next step, based on these findings, is for the scientists to seek authorization from the U.S. Food and Drug Administration (FDA) to conduct clinical trials on the silver-antibiotics formula. They also hope to work with the University of Florida’s Innovate program to patent an antimicrobial product that contains silver nanoparticles.

“Perhaps there was a reason for gold and silver money, silver eating utensils, and the current use of silver in burn dressing,” one commenter wrote about the history of use for silver, gold, and other natural metals.

“They have discovered something that has been known for hundreds of years but has recently been hidden by Big Pharma.”

Another wrote that colloidal silver can be made at home fairly easily without the need to purchase it as a patented drug formula.

“It works against bacteria, virus, and fungus,” this person added about homemade colloidal silver. “The U.S. Navy has experimented with this, and it is also used by the ‘silver spoon’ rich.”

Someone else joked that the new research “gives new meaning to being fed with a silver spoon.”

Sources for this article include:

Mining.com

NaturalNews.com

At 82, he’s as fit as a 20-year-old. His body holds clues to healthy aging

At 82, he’s as fit as a 20-year-old. His body holds clues to healthy aging.© Clarissa Brusco/Clarissa Brusco

As a model of successful aging, you can’t beat 82-year-old Juan López García.

Really, you can’t beat him.

Sixteen years ago, at age 66, López García first tried running a mile. He’d recently retired after spending his entire working life as a car mechanic in Toledo, Spain. In all those years, he’d never trained as an athlete or exercised much at all.

He couldn’t finish that first mile. He could barely start it.

Now, at age 82, López García is the world record holder in the 80-to-84 age group for the 50-kilometer (31-mile) ultramarathon. In 2024, he also won the world marathon championship for his age group, with a time of 3:39:10, setting a European record in the process.

His outsize success caught the attention of a group of European scientists who study aging. They invited López García to their lab for extensive testing. Their findings, published in January in Frontiers in Physiology, are, at once, revealing and “inspiring,” said Julian Alcazar, an exercise scientist at the University of Castilla-La Mancha in Spain and a co-author of the study.

The researchers found that López García has the highest aerobic fitness recorded in an octogenarian, matching that of healthy 20-to-30-year-old men. His muscles also absorb and use oxygen unusually well. But in other ways, his biology, biomechanics and training seem relatively ordinary.

Taken as a whole, López García’s physiology and performance in his 80s may help upend some common assumptions about what’s possible and normal as we age, the researchers concluded, including whether it’s ever too late for the rest of us to tackle that first mile.

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The Major Controversy Surrounding Grocery Store Eggs Right Now (No, It’s Not a Recall)

Eggs are a staple on many people’s weekly grocery list.

n the last year amid skyrocketing egg prices and multiple recalls, shoppers

have been left weary on what to buy or whether they can even secure a carton.

Now, eggs are under fire for a different reason.

A social media scandal has the company Vital Farmsin hot water.

It all started when Instagram user @zephzoid broke the story in

his self-titled “exposé” video, revealing that a study found some

controversial findings about Vital Farms eggs. People on social

media swiftly went into a frenzy, with some expressing disappointment

and encouraging others to boycott the company.

What is situs inversus? The rare condition Catherine O'Hara suffered as she dies at age 71

The above graphic shows normal anatomy (left, situs solitus) and the flipped anatomy (right) that is observed in people with situs inversus

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Which types of physical activity may help prolong life span?

Design by MNT; Photography by Halfpoint Images/Getty Images & Rob and Julia Campbell/Stocksy

A mix of healthy lifestyle choices, such as getting enough physical activity, can help people live a longer, healthier life.
However, the types of physical activity best for longevity remain underexplored.
A new study says that regularly participating in a variety of different types of physical activity, such as running, cycling, and swimming, may be the best way to help prolong your lifespan.

Research so far has suggested that a mix of healthy lifestyle choices — like eating a healthy dietTrusted Source, not smoking, managing stress, getting enough sleep, and getting enough physical activity — can help us all live longer, healthier lives.

What can be confusing is knowing what types of physical activity are best for longevity.

A recent study published in BMJ Medicine helps answer that question by finding that regularly engaging in a variety of physical activities may be the best way to prolong your life span.

Your office water cooler could be hiding a silent killer, study reveals

They found that water dispensers, in many cases, contained more bacteria than the tap water sources supplying them. Soda machines were also found to have bacterial contamination.

In some cases, bacterial growth emerged just days after the machines had been disinfected.

Microbes infesting the machines included fecal coliform, bacteria linked to human and animal waste that can raise the risk of gastrointestinal illnesses such as nausea and vomiting. In rare cases, infections with the bacteria can be deadly.

Dr Ryan Sinclair, an environmental microbiology expert who was involved in the study, said: 'Filtering out residual chlorine that's in water makes an ideal situation for bacteria to grow. You've got to clean the tubes and change the filters regularly.'

Bacteria are normally not in tap water sources because of trace levels of chlorine, which kills off the microbes.

But in water coolers and dispensers, chlorine can be filtered out, allowing bacteria to grow, while damp surfaces on nozzles can also trigger its growth.

Staff can also fail to regularly clean or change water filters in the machines, which the experts warned could result in filters becoming a breeding ground for bacteria.

The authors said that their study aimed to boost awareness around the risks from water dispensers and to encourage regular cleaning of the machines.

Led by Dr Thomas Hile, a water quality expert at Crafton College Hills, California, the scientists said the machines should be cleaned every two to four weeks, or every week in the case of regular usage.

In the study, published in the journal AIMS Microbiology, researchers analyzed studies on bacterial contamination in water dispensers or coolers.

For the papers that were studied, researchers had tested the inside of water coolers and their nozzles, or the point from which they dispense water, for bacteria.

The studies also looked at water dispensers that were directly connected to the tap water supply and those that have a large bottle of distilled water placed on top.

Overall, the researchers said their study showed that the surfaces of water dispensers could become contaminated with biofilms, a slimy, protective layer made by microorganisms, which allow bacteria to proliferate and thrive.

Bacteria had been found growing on the machines, in some cases, just a few days after they had been cleaned (stock image)

This could happen on the outside of the machines, inside their water containers, tubes or on their nozzles used to fill bottles.

Their paper cited a study published in Italy in 1987, which found that nozzles from hot drinks vending machines had 100-fold more bacteria than other areas on the same water dispenser.

The dangerous bacteria lurking in hand dryers: Experiment reveals organisms may be in dryers at public toilets, gas stations and movie theaters

It also cited a 2020 paper from researchers in the UK, which found that inadequate cleaning of these machines may result in biofilm formation.

On soda fountains, their study cited a 2010 paper from researchers in Virginia, which found that 48 percent of the 20 self-service soda machines it sampled were contaminated with coliform bacteria, or bacteria typically found in human feces that can cause gastrointestinal illnesses.

In some cases, this included E. coli, which is a type of coliform bacteria.

Additionally, the researchers cited a study on 36 soda machines in Las Vegas found 88 percent of the soda dispensers were contaminated with coliforms.

The researchers of the new review said: 'The presence of microbial contaminants in soda fountains should not be overlooked.

'The lack of residual disinfectant, such as chlorine in water dispensers, allows microorganisms to regrow downstream of filtration.'

They added: 'Unlike municipal water distribution, where residual chlorine suppresses microbial proliferation, water dispensers supply water that is typically free of disinfectant.

'This creates favorable conditions for microbial survival, particularly within internal tubing and dispensing outlets.'

Balance of Nature has faced multiple lawsuits and regulatory actions for making false and misleading claims

Balance of Nature has faced multiple lawsuits and regulatory actions for making false and misleading claims about the health benefits of its dietary supplements, including a class action settlement and action from the FDA and California state prosecutors.

Key Legal Actions and Settlements

Nationwide Class Action Lawsuit (In Progress): A $9.95 million settlement is in progress to resolve a class action suit alleging the company falsely advertised health benefits and the nutritional value of its products.
- Eligibility: U.S. consumers who purchased Balance of Nature products between March 28, 2019, and October 27, 2025, are eligible to file a claim.
- Compensation: Eligible consumers can receive up to $30 with proof of purchase or $8 without proof of purchase.
- Claim Deadline: The deadline to file a claim is March 11, 2026. More information and the claim form are available on the Supplements Settlement website.
California District Attorneys' Lawsuit (Settled): In July 2023, Balance of Nature (Evig LLC) agreed to a $1.1 million settlement with a task force of California district attorneys.
- Allegations: The lawsuit claimed the company made unsubstantiated claims that its products could treat or cure serious diseases (e.g., cancer, diabetes, lupus) and violated California's automatic renewal laws.
- Outcome: The settlement included $850,000 in civil penalties and $250,000 in customer restitution for California residents who purchased products in the prior six years.
FDA and Department of Justice Action: In November 2023, a federal judge entered a consent decree against Balance of Nature's manufacturer and distributor, ordering them to halt all sales and production until they came into compliance with federal regulations.
- Reasoning: The FDA found the company was manufacturing products in violation of quality control standards and marketing them as unapproved drugs capable of treating diseases like COVID-19, cancer, and heart disease.
- Current Status: Balance of Nature resumed operations shortly after, following the submission of an "Action Plan" to the FDA and the hiring of independent experts to ensure compliance with manufacturing and labeling rules.

The core of the lawsuits centers on allegations that the company made numerous health claims without adequate scientific evidence, overstating the nutritional benefits of the supplements and equating them to whole food consumption.

Rapid brain aging occurs at three distinct ages, scientists discover: Here’s how to slow it down

A new study has revealed that brain aging peaks at three distinct ages: 57, 70 and 78.

The research, published in Nature this month, analyzed the brain scans of more than 10,000 adults and looked for changes in their blood protein.

They identified 13 blood proteins that were associated with the “brain age gap,” an indicator for cognitive decline, and found “brain age-related change peaks at 57, 70 and 78” years of age, according to the report.

Keto’s HDAC Promise Meets Real World Data | Mercola Cellular Wisdom

The foods that actually block the body from gaining weight

Beans, lentils and plum juice could help prevent you from gaining weight, a study suggests, even if you follow a high-fat diet.

Researchers at the University of Utah tracked mice on a high-fat diet for eight weeks, and fed some supplements of Turicibacter, a bacteria found in the human gut.

Among mice without supplements, the researchers said they gained about 25 percent of their bodyweight over the study period.

For comparison, however, those that received the Turicibacter supplement only gained about 10 percent of their bodyweight.

Researchers said in a press release that the results opened the door to potentially using Turicibacter to prevent weight gain in humans.

Supplements containing Turicibacter are not yet widely available, but previous research suggested people could boost the bacteria's population in their gut by consuming a high-fiber diet rich in fruits and vegetables as fiber provides fuel for micro-organisms.

A previous study also found that plum juice raised Turicibacter levels in the guts of obese rats, which researchers said may be because it contains polyphenolic compounds that can boost good microbes in the gut.

Experts warn that the bacteria does not grow in people who follow a high-fat diet because it is unable to survive in high-fat environments.

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Weightlifting beats running for blood sugar control, researchers find

Virginia Tech scientists at the Fralin Biomedical Research Institute show that resistance training outperforms endurance exercise in improving insulin sensitivity in obesity and Type 2 diabetes models.

Running may help burn calories, but when it comes to preventing diabetes and obesity, pumping iron might have the edge, according to preclinical findings from Virginia Tech scientists at the Fralin Biomedical Research Institute at VTC.

The research, published Oct. 30 in the Journal of Sport and Health Science, compared the effects of endurance and resistance exercise in mice fed a high-fat diet, a widely used model of obesity, hyperglycemia, and Type 2 diabetes.

A team led by exercise medicine researcher Zhen Yan found that while both running and weightlifting helped the body clear excess sugar from the blood, resistance training was more effective in reducing subcutaneous and visceral fat, improving glucose tolerance, and lowering insulin resistance — key factors in preventing and managing diabetes.

“We all want to live a long, healthy life,” said Yan, professor and director of the institute’s Center for Exercise Medicine Research. “We all know the benefits of regular exercise. There is plenty of evidence in humans that both endurance exercise, such as running, and resistance exercise, such as weightlifting, are effective in promoting insulin sensitivity.”

But while both support metabolic function, a rigorous side-by-side comparison was lacking. Is one type of exercise better than the other?

What they did>>>>>>>>

Trump Admin Announces New Dietary Guidelines

The administration of President Donald Trump on Wednesday announced a new slate of dietary guidelines that recommends Americans eat more protein and less sugar than previously advised and that consumers avoid highly processed foods to achieve a healthy diet.

The guidelines are the latest product of the Trump administration's "Make America Healthy Again" agenda, named for the social movement that backs Health Secretary Robert F. Kennedy Jr.

He and other officials, including Agriculture Secretary Brooke Rollins, have implemented MAHA policy goals such as curbing childhood vaccines and restricting access to unhealthy foods for people receiving food ‍stamps.

Kennedy and Rollins had pledged to simplify the guidelines and remove what they described as the undue influence of food companies over their recommendations.

The guidelines are ‍published every five years by the Department of Health and Human Services and the Department of Agriculture.

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