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WEDNESDAY, Feb. 27 (HealthDay News) -- Curcumin, an ingredient in the curry spice tumeric, can reduce heart enlargement and may lower the risk of heart failure, Canadian researchers say.
The scientists at the Peter Munk Cardiac Centre of the Toronto General Hospital tested the effects of curcumin in mice with enlarged hearts (hypertrophy) and found it could prevent and reverse the condition, restore heart function, and reduce scar formation. The study was published in the February issue of the Journal of Clinical Investigation.
If human clinical trials support these findings, curcumin-based treatments may provide a safe and inexpensive new option for patients with heart enlargement, according to the researchers.
They said curcumin works directly in the cell nucleus by preventing abnormal unraveling of the chromosome under stress and preventing excessive abnormal protein production.
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