Ovarian cancers may begin in the fallopian tube

NEW YORK (Reuters Health) - New research suggests that fallopian tube cells rather than ovarian surface cells are the probable site of origin of most cases of ovarian serous carcinoma, the most common type of ovarian cancer.

This finding may lead to earlier detection, as well as better treatment and perhaps prevention, of ovarian cancer, Dr. Keren Levanon of the Dana Farber Cancer Institute in Boston told the annual gathering of the American Association for Cancer Research in San Diego.

As there is no early diagnostic test for ovarian cancer, roughly 80 percent of cases are diagnosed at a very late stage. "One fascinating fact," Levanon highlighted, "is that when you diagnose ovarian cancer you find massive invasive tumors on the surface of the ovary -- usually the tumor does not invade the ovary -- but you never find early pre-invasive in situ tumors."

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